STUDY OF THE EFFECT OF VITAMIN E ON LIPID PEROXIDATION AND ANTIOXIDANT PROTECTION IN RATS WITH EXPERIMENTAL ACUTE PANCREATITIS
DOI:
https://doi.org/10.17605/OSF.IO/DV9QFKeywords:
experimental acute pancreatitis, antioxidant system, catalase, malondialdehyde, superoxide dismutase, vitamin E.Abstract
To the article Shukurov I.B. "Effect of tocopherol on lipid peroxidation and antioxidant defense in rats with acute pancreatitis"
This article presents data on the effect of tocopherol on a number of biochemical parameters, in particular, on the state of lipid peroxidation and AOP in dynamics in rats with OP. Animals are divided into 4 groups. The results obtained are compared with those of group 1 (healthy animals). Experimental OP in mice was characterized by an increase in lipid peroxidation, as well as a decrease in the activity of AOD enzymes during all periods of the study. Preliminary saturation of the organism of animals of the 4th group (OP + E) with tocopherol (vitamin E) at a dose of 0.5 mg per 100 g of body weight for 14 days led to an increase in antioxidant protection and inhibition of LPO processes, which indicates the bioprotective and therapeutic effects of tocopherol in OP as a result of induction of AOD enzymes in experimental animals.
