NON-ALCOHOLIC FATTY LIVER DISEASE

Abstract

In recent decades, there has been an increase in non-alcoholic fatty liver disease (NAFLD), which not only leads to a decrease in the quality of life of patients, but also affects their life expectancy. Fatty hepatosis or non—alcoholic fatty liver disease (NAFLD, steatosis) is a disease in which excessive accumulation of fats (mainly triglycerides) is observed in the liver. Normally, there is a certain amount of fat in the liver, but when exposed to certain pathological factors, the balance between the synthesis and utilization of fats may be disturbed. The prevalence of NAFLD is higher among men and increases with age, due to socio-economic differences and lifestyle. In the general population of Western countries, the prevalence of NAFLD is 20-30%, of which 2-3% of cases have a progressive course of liver disease with transformation into non-alcoholic steatohepatitis (NASH), cirrhosis of the liver, hepatocellular carcinoma.