ABOUT MODELS OF EXPERIMENTAL DEVELOPMENT OF DIABETES 2

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Kosimova Dilnoza Sayotovna

Abstract

The paper analyzes the development models of type 2 diabetes mellitus (DM2). Rodents are best suited for this (mainly mice, including outbred lines), and rats, which have become more widely used recently. As for models of metabolic syndrome and obesity, diet-induced models are also closest in etiology and development mechanisms to DM2 in humans, among which high-fat diets (HFAs) enriched with sucrose or fructose are the most effective.

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