PERSONALIZED MEDICINE IN CARDIOLOGY: STATE OF THE PROBLEM AND OUTLOOK
DOI:
https://doi.org/10.17605/OSF.IO/3J5HWKeywords:
pharmacogenetics, biomarkers, personalized medicine, genetic information, genetic testing.Abstract
Personalized medicine emerged about three decades ago. Even then, it interested many scientists, researchers, doctors. However, only after the complete discovery of the human genome in 2001, personalized medicine began to make it possible for some pathologies (oncology, rheumatology, cardiology) to select the most effective treatment with minimal adverse drug reactions for a particular patient. The ability to own genetic information gives a chance to suspect, predict, predict the onset of the disease. Personalized medicine is able in some cases to tell exactly whether a drug will work for a given patient, bringing us closer to “treating not the disease, but the patient.” But doctors to this day, to determine risk factors, are guided by the individual characteristics of the patient, such as age, gender, body weight, concomitant diseases, and, based on this, prescribe drugs, adjust the dose, and change the treatment regimen if ineffective.