THE EFFECTIVENESS OF SELENIUM IN REDUCING THE RISK OF OXIDATIVE STRESS

Abstract

The purpose of this study was to examine the potential protective effect of selenium against potassium dichromate toxicity and to evaluate the toxicity of selenium.Potassium dichromate in male rats. One indicator of oxidative stress is the presence of statistically significant levels of mal in liver and kidney tissues as a result of the ability of potassium dichromate to produce stress-causing electrolytes. Increased oxidized fats, decreased high-density fats, and increased low-density fats have been observed in male rats. Liver and kidney cells are injured, as Decreased activity of catalase and glutathione enzymes in the liver and kidneys is observed. High levels of tbars were observed in the liver and kidneys, with histological changes in the kidneys and liver confirming enzymatic changes. On the other hand, histological sections of the kidneys of the treated group showed shrinkage of the renal glomeruli and dilatation of Bowman's cyst caused by potassium dichromate, congestion and hemorrhage of blood vessels close to the body of Malpighi, and increased thickness of its walls. The presence of protein casts in the lumen of renal tubules, intratubular bleeding, dilatation, leukocyte infiltration and 1. This study was behaved on adult male albino rats (24 mice), divided into 4 equal groups (6 mice) for each group. at the latest of the experiment. Blood was drawn from the ear vein of mice in all groups for evaluation.Biochemical parameters were collected in blood scans and liver and kidney samples from mice for histological examination.