EFFICIENCY OF TREATMENT FOR RECURRENT AFTHOUS STOMATITIS OF THE OROPHARYNGIAL REGION IN PATIENTS WITH CHRONIC CHOLECYSTITIS

Abstract

Chronic recurrent aphthous stomatitis (CRAS) is a chronic inflammatory disease of the oral mucosa and characterized by the appearance of aphthous ulcers with a long course and periodic remissions and exacerbations. Much attention is paid to somatic diseases, which aggravate the course of CRAS. V.A. Epishev observed chronic recurrent aphthous stomatitis in gastrointestinal diseases in 15.2% of cases, according to G.V. Banchenko - 12%. The factors provoking relapses include microorganisms that in the process of vital activity, especially during death, release bacterial endotoxins, which have both antigenic and toxic features. An increased process of tissue alteration during the activation of catabolic processes is one of the causes of endogenous intoxication (Sidelnikova V.I., Chernitskiy A.E., Retsky M.I., 2015). In chronic cholecystitis, CRAS is often observed in the oropharyngeal region. The drug Baktizidime was introduced as the treatment regimen of CRAS of the oropharyngial region of the main group and the drug Eludril into the comparison group.