STUDY OF FLAVONOID COMPOSITION AND BIOLOGICAL ACTIVITY OF LEAVES OF MAPLE SEMENOV ACER SEMENOVII

Abstract

The results of a study of the content of polyphenolic compounds and their antioxidant activity in the plant - Acer semenovii - family Aceraceae Juss., growing in the mountainous regions of the Tashkent region of the Republic of Uzbekistan are presented. The collection of raw materials took place in the spring at the end of April - beginning of May and in the fall at the beginning of September 2022-2023. The conditions for the isolation of polyphenolic compounds from the leaves of Maple Semenov under various conditions were selected. It has been shown that the optimal content of polyphenols is extracted with 40% ethyl alcohol, followed by fractionation of the aqueous residue with ethyl acetate and precipitation with chloroform. It was shown that in plants collected in the spring, the yield of total polyphenols was 8.9% of the air-dry mass of the raw material. Chromatographic methods (BC and TLC) revealed that the leaves of plants collected in the spring contain more polyphenols than those of plants collected in early autumn. Compounds belonging to the class of poliphenolic compounds, flavonols, phenolic acids and flavan-3-ols were found in this plant.