PATHOPHYSIOLOGICAL MECHANISM OF GROWTH HORMONE CONTROL IN THE TREATMENT OF HEREDITARY DISEASES IN CHILDREN

Abstract

Growth hormone (GH) deficiency is the most common pituitary hormone deficiency in children and can occur in isolation or in combination with other pituitary hormone deficiencies. In typical cases, growth hormone deficiency in children is characterized by an abnormally low growth rate and short stature while maintaining normal body proportions. Diagnostics include measuring pituitary hormone levels and CT or MRI to detect structural abnormalities of the pituitary gland or brain tumors. Treatment usually includes hormone replacement therapy and removal of the tumor if it is causing the disorder.