CIRCADIAN RHYTHM BLOOD PRESSURE IN PATIENTS HEART FAILURE IN RENAL DYSFUNCTION

Abstract

Despite the frequent combination of chronic heart failure (CHF) with chronic kidney disease (CKD), the features of the circadian rhythm of blood pressure in patients with CHF associated with CKD remain insufficiently studied. 117 patients with CHF were examined.In 56 patients, the glomerular filtration rate (GFR) was higher than 60 ml/min/1.73 m2, a moderate decrease in GFR from 45 to 59 ml/min/1.73 m2 was found in 37 patients, in 24 patients there was a pronounced decrease in GFR - below 45 ml/min/1.73m2. The correlation of the degree of nocturnal decline was revealed SBP and DBP with GFR. Multivariate regression analysis confirmed an independent relationship between the decrease in GFR of less than 45 ml/min/1.73m2 and the degree of nocturnal decrease in SBP and DBP. The results of the study indicate significant violations of the circadian rhythm of blood pressure in patients with CHF associated with CKD.