THE PROBLEM OF IRRADIATION IN MODERN MORPHOLOGY

Abstract

The issue of irradiation in modern morphology is a topic of increasing concern and research due to its implications for tissue preservation, experimental reproducibility, and occupational safety. This article provides a comprehensive overview of the challenges posed by irradiation in morphological studies, examining its effects on tissue structure, cellular morphology, antigenicity, and molecular integrity. Through a critical analysis of existing literature and experimental findings, the article explores the mechanisms underlying radiation-induced tissue damage and the factors influencing the susceptibility of different tissues to irradiation. Moreover, the article discusses strategies for mitigating the adverse effects of irradiation on morphological specimens, including optimization of irradiation protocols, selection of appropriate fixation methods, and implementation of quality control measures. By synthesizing current knowledge and best practices, this article aims to inform researchers, histotechnologists, and pathologists about the complexities of irradiation in modern morphology and facilitate the development of standardized guidelines for tissue processing and analysis.